Phenotypes associated with this allele

• Allele Symbol: Aldh16a1^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4432547
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aldh16a1^tm1a(EUCOMM)Wtsi/Aldh16a1^tm1a(EUCOMM)Wtsi	C57BL/6N-Aldh16a1^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5608380
hm2	Aldh16a1^tm1a(EUCOMM)Wtsi/Aldh16a1^tm1a(EUCOMM)Wtsi	C57BL/6NTac-Aldh16a1^tm1a(EUCOMM)Wtsi/WtsiH	MGI:6276307

Genotype
MGI:5608380

hm1

• Allelic Composition: Aldh16a1^{tm1a(EUCOMM)Wtsi}/Aldh16a1^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Aldh16a1^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0091_2_D04

Data Sources

IMPC Data for Aldh16a1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating sodium level ( J:211773 )

IMPC - WTSI

decreased circulating chloride level ( J:211773 )

IMPC - WTSI

vision/eye

abnormal retina morphology ( J:211773 )

♂

IMPC - WTSI

Genotype
MGI:6276307

hm2

• Allelic Composition: Aldh16a1^{tm1a(EUCOMM)Wtsi}/Aldh16a1^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6NTac-Aldh16a1^{tm1a(EUCOMM)Wtsi}/WtsiH
• Cell Lines: EPD0091_2_D04

homeostasis/metabolism

abnormal ion homeostasis ( J:255311 )

• a reduction in ion abundance in blood plasma is seen in mutant mice

abnormal lipid homeostasis ( J:255311 )

• an altered lipid profile in blood plasma from mutant mice is seen