All Phenotypes Sesn3<tm1a(EUCOMM)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sesn3^{tm1a(EUCOMM)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4432370

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sesn3^{tm1a(EUCOMM)Wtsi}/Sesn3^{tm1a(EUCOMM)Wtsi}	C57BL/6N-Sesn3^{tm1a(EUCOMM)Wtsi}/Wtsi	MGI:5781735
cx2	Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Sesn3^{tm1a(EUCOMM)Wtsi}/Sesn3^{tm1a(EUCOMM)Wtsi}	involves: 129P2/OlaHsd * C57BL/6N	MGI:5444498

Allelic Composition	Sesn3^{tm1a(EUCOMM)Wtsi}/Sesn3^{tm1a(EUCOMM)Wtsi}
Genetic Background	C57BL/6N-Sesn3^{tm1a(EUCOMM)Wtsi}/Wtsi
Cell Lines	EPD0051_5_C06

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sesn3^{tm1a(EUCOMM)Wtsi} mutation (1 available); any Sesn3 mutation (26 available)

Data Sources

IMPC Data for Sesn3

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased circulating sodium level ( J:175295 )

IMPC - WTSI

increased circulating chloride level ( J:175295 )

IMPC - WTSI

Allelic Composition	Sesn2^{Gt(RRJ141)Byg}/Sesn2^{Gt(RRJ141)Byg} Sesn3^{tm1a(EUCOMM)Wtsi}/Sesn3^{tm1a(EUCOMM)Wtsi}
Genetic Background	involves: 129P2/OlaHsd * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sesn2^{Gt(RRJ141)Byg} mutation (1 available); any Sesn2 mutation (114 available)
Sesn3^{tm1a(EUCOMM)Wtsi} mutation (1 available); any Sesn3 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

impaired glucose tolerance ( J:189021 )

• spontaneous in mice fed a low fat diet

insulin resistance ( J:189021 )

• spontaneous in mice fed a low fat diet

liver/biliary system

liver/biliary system phenotype ( J:189021 )

N	• mice do not develop hepatosteatosis

growth/size/body

growth/size/body region phenotype ( J:189021 )

N	• mice exhibit normal weight

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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