Phenotypes associated with this allele

• Allele Symbol: Ccdc57^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4431914
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccdc57^tm1a(EUCOMM)Wtsi/Ccdc57^tm1a(EUCOMM)Wtsi	B6JTyr;B6N-Ccdc57^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5781589
ht2	Ccdc57^tm1a(EUCOMM)Wtsi/Ccdc57^+	B6JTyr;B6N-Ccdc57^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5781588

Genotype
MGI:5781589

hm1

• Allelic Composition: Ccdc57^{tm1a(EUCOMM)Wtsi}/Ccdc57^{tm1a(EUCOMM)Wtsi}
• Genetic Background: B6JTyr;B6N-Ccdc57^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0037_3_D11

Data Sources

IMPC Data for Ccdc57

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal cranium morphology ( J:175295 )

♀

IMPC - WTSI

skeleton

abnormal cranium morphology ( J:175295 )

♀

IMPC - WTSI

Genotype
MGI:5781588

ht2

• Allelic Composition: Ccdc57^{tm1a(EUCOMM)Wtsi}/Ccdc57⁺
• Genetic Background: B6JTyr;B6N-Ccdc57^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0037_3_D11

Data Sources

IMPC Data for Ccdc57

growth/size/body

decreased body weight ( J:175295 )

IMPC - WTSI

hematopoietic system

decreased mean corpuscular hemoglobin ( J:175295 )

♀

IMPC - WTSI

homeostasis/metabolism

decreased circulating glucose level ( J:175295 )

IMPC - WTSI

decreased circulating potassium level ( J:175295 )

IMPC - WTSI

increased circulating sodium level ( J:175295 )

IMPC - WTSI