Phenotypes associated with this allele

• Allele Symbol: Prmt7^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4431677
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prmt7^tm1a(EUCOMM)Wtsi/Prmt7^tm1a(EUCOMM)Wtsi	B6JTyr;B6N-Prmt7^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5781711
ht2	Prmt7^tm1a(EUCOMM)Wtsi/Prmt7^+	B6JTyr;B6N-Prmt7^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5781710

Genotype
MGI:5781711

hm1

• Allelic Composition: Prmt7^{tm1a(EUCOMM)Wtsi}/Prmt7^{tm1a(EUCOMM)Wtsi}
• Genetic Background: B6JTyr;B6N-Prmt7^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0070_4_F09

Data Sources

IMPC Data for Prmt7

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

retroesophageal right subclavian artery ( J:239583 )

DMDD

absent segment of posterior cerebral artery ( J:239583 )

DMDD

abnormal vertebral artery morphology ( J:239583 )

DMDD

abnormal liver vasculature morphology ( J:239583 )

DMDD

abnormal vitelline vein connection ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal ductus venosus valve morphology ( J:239583 )

DMDD

abnormal ductus venosus valve topology ( J:239583 )

DMDD

abnormal inferior vena cava morphology ( J:239583 )

DMDD

dual inferior vena cava ( J:239583 )

DMDD

abnormal coronary sinus connection ( J:239583 )

DMDD

abnormal inferior vena cava valve morphology ( J:239583 )

DMDD

abnormal aortic valve morphology ( J:239583 )

DMDD

hemopericardium ( J:239583 )

DMDD

embryo

abnormal vitelline vein connection ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal thymus topology ( J:239583 )

DMDD

abnormal gallbladder morphology ( J:239583 )

DMDD

growth/size/body

decreased lean body mass ( J:175295 )

IMPC - WTSI

thoracoschisis ( J:239583 )

DMDD

heterochrony ( J:239583 )

DMDD

hematopoietic system

abnormal thymus topology ( J:239583 )

DMDD

decreased erythrocyte cell number ( J:175295 )

♂

IMPC - WTSI

homeostasis/metabolism

hemopericardium ( J:239583 )

DMDD

subcutaneous edema ( J:239583 )

DMDD

immune system

abnormal thymus topology ( J:239583 )

DMDD

blood in lymph vessels ( J:239583 )

DMDD

integument

subcutaneous edema ( J:239583 )

DMDD

liver/biliary system

abnormal liver vasculature morphology ( J:239583 )

DMDD

abnormal gallbladder morphology ( J:239583 )

DMDD

neoplasm

increased trigeminal neuroma incidence ( J:239583 )

DMDD

embryo tumor ( J:239583 )

DMDD

nervous system

absent segment of posterior cerebral artery ( J:239583 )

DMDD

increased trigeminal neuroma incidence ( J:239583 )

DMDD

abnormal hypoglossal nerve topology ( J:239583 )

DMDD

skeleton

abnormal rib morphology ( J:175295 , J:239583 )

DMDD (J:239583)

IMPC - WTSI ♀ (J:175295)

abnormal cervical rib ( J:239583 )

DMDD

Genotype
MGI:5781710

ht2

• Allelic Composition: Prmt7^{tm1a(EUCOMM)Wtsi}/Prmt7⁺
• Genetic Background: B6JTyr;B6N-Prmt7^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0070_4_F09

Data Sources

IMPC Data for Prmt7

growth/size/body

increased body weight ( J:175295 )

IMPC - WTSI