All Phenotypes Plppr4<tm2.1Roni> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Plppr4^tm2.1Roni
targeted mutation 2.1, Robert Nitsch
MGI:4431224

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Plppr4^tm2.1Roni/Plppr4^tm2.1Roni	involves: 129P2/OlaHsd * C57BL/6	MGI:4431243

Allelic Composition	Plppr4^tm2.1Roni/Plppr4^tm2.1Roni
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plppr4^tm2.1Roni mutation (0 available); any Plppr4 mutation (29 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:157318 )

N	• at P21, mice do not exhibit seizures

increased excitatory postsynaptic current amplitude ( J:157318 )

• at P20, CA1 neurons electroporated with a cre recombinase construct in utero exhibit an increase in stimulus-evoked excitatory postsynaptic current amplitudes compared wild-type cells

increased miniature excitatory postsynaptic current frequency ( J:157318 )

• CA1 neurons electroporated with a cre recombinase construct in utero exhibit an increase in miniature excitatory postsynaptic current frequency compared with wild-type cells

behavior/neurological

behavior/neurological phenotype ( J:157318 )

N	• at P21, mice do not exhibit seizures

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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