Phenotypes associated with this allele

• Allele Symbol: Hipk2^tm1Afus
• Allele Name: targeted mutation 1, Alfredo Fusco
• Allele ID: MGI:4429497
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hipk2^tm1Afus/Hipk2^tm1Afus	involves: 129X1/SvJ * C57BL/6	MGI:4429498

Genotype
MGI:4429498

hm1

• Allelic Composition: Hipk2^tm1Afus/Hipk2^tm1Afus
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:156574 )

• slight reduction in motility of the posterior limbs

limb grasping ( J:156574 )

• in about 15% of mice

cellular

abnormal cell cycle ( J:156574 )

• increase in number of MEFs in the G0/G1 phase of the cell cycle

decreased cell proliferation ( J:156574 )

• reduced proliferation of MEFs

growth/size/body

decreased birth weight ( J:156574 )

decreased body weight ( J:156574 )

• body weight of 2-month-old mice shows a reduction of nearly 40%