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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ift172tm1.2Rama
targeted mutation 1.2, Richard A Maurer
MGI:4420980
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ift172tm1.2Rama/Ift172tm1.2Rama involves: 129S4/SvJaeSor * 129X1/SvJ * BALB/c * C57BL/6 MGI:4420984
cn2
 		Ift172tm1.1Rama/Ift172tm1.2Rama
Tg(Prrx1-cre)1Cjt/0 		involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * SJL/J MGI:4420983


Genotype
MGI:4420984
hm1
Allelic
Composition		 Ift172tm1.2Rama/Ift172tm1.2Rama
Genetic
Background		 involves: 129S4/SvJaeSor * 129X1/SvJ * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift172tm1.2Rama mutation (0 available); any Ift172 mutation (73 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo
abnormal embryo development ( J:156426 )
• mice are severely malformed at E12

nervous system




Genotype
MGI:4420983
cn2
Allelic
Composition		 Ift172tm1.1Rama/Ift172tm1.2Rama
Tg(Prrx1-cre)1Cjt/0
Genetic
Background		 involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift172tm1.1Rama mutation (1 available); any Ift172 mutation (73 available)
Ift172tm1.2Rama mutation (0 available); any Ift172 mutation (73 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
polydactyly ( J:156426 )
• a single extra digit on each forelimb and hindlimb




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory