All Phenotypes Rnf139<tm1(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rnf139^{tm1(KOMP)Wtsi}
targeted mutation 1, Wellcome Trust Sanger Institute
MGI:4419541

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf139^{tm1(KOMP)Wtsi}/Rnf139^{tm1(KOMP)Wtsi}	involves: C57BL/6J * C57BL/6N	MGI:5827554

Allelic Composition	Rnf139^{tm1(KOMP)Wtsi}/Rnf139^{tm1(KOMP)Wtsi}
Genetic Background	involves: C57BL/6J * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnf139^{tm1(KOMP)Wtsi} mutation (0 available); any Rnf139 mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

liver/biliary system

increased hepatocyte apoptosis ( J:231404 )

• in mice fed a high-fat or a methionine and choline deficient diet

liver inflammation ( J:231404 )

• augmented in mice fed a methionine and choline deficient diet

liver fibrosis ( J:231404 )

• augmented in mice fed a methionine and choline deficient diet

immune system

liver inflammation ( J:231404 )

• augmented in mice fed a methionine and choline deficient diet

cellular

increased hepatocyte apoptosis ( J:231404 )

• in mice fed a high-fat or a methionine and choline deficient diet

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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