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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Bola2tm1(KOMP)Wtsi
targeted mutation 1, Wellcome Trust Sanger Institute
MGI:4419429
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Bola2tm1(KOMP)Wtsi/Bola2tm1(KOMP)Wtsi C57BL/6N-Bola2tm1(KOMP)Wtsi/Nju MGI:5797405
ht2
Bola2tm1(KOMP)Wtsi/Bola2+ C57BL/6N-Bola2tm1(KOMP)Wtsi MGI:8209495


Genotype
MGI:5797405
hm1
Allelic
Composition
Bola2tm1(KOMP)Wtsi/Bola2tm1(KOMP)Wtsi
Genetic
Background
C57BL/6N-Bola2tm1(KOMP)Wtsi/Nju
Cell Lines EPD0384_6_A09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bola2tm1(KOMP)Wtsi mutation (0 available); any Bola2 mutation (6 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system

homeostasis/metabolism

integument

pigmentation




Genotype
MGI:8209495
ht2
Allelic
Composition
Bola2tm1(KOMP)Wtsi/Bola2+
Genetic
Background
C57BL/6N-Bola2tm1(KOMP)Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bola2tm1(KOMP)Wtsi mutation (0 available); any Bola2 mutation (6 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• in adult females, total brain area is reduced by 9% relative to wild-type females
• in adult males, the area of the dorsal third ventricle is smaller by no less than 40% relative to wild-type males
• in adult males, the area of the soma of the corpus callosum is decreased by 10% while the height of the same structure is reduced by 11% relative to wild-type males
• in adult females, the height of the genu of the corpus callosum is reduced by 15% while the soma of the corpus callosum is smaller by 14% for its area, 11% for its width and 10% for its height
• in adult males, the area of the hippocampus is smaller by 12% relative to wild-type males
• in adult females, the height of the secondary somatosensory cortex is thinner by 11% relative to wild-type females





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory