Phenotypes associated with this allele

• Allele Symbol: Coro1c^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4419168
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Coro1c^tm1a(KOMP)Wtsi/Coro1c^tm1a(KOMP)Wtsi	C57BL/6N-Coro1c^tm1a(KOMP)Wtsi/Wtsi	MGI:5883878
ht2	Coro1c^tm1a(KOMP)Wtsi/Coro1c^+	C57BL/6N-Coro1c^tm1a(KOMP)Wtsi/Wtsi	MGI:6771964

Genotype
MGI:5883878

hm1

• Allelic Composition: Coro1c^{tm1a(KOMP)Wtsi}/Coro1c^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Coro1c^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0343_2_A06

Data Sources

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal vertebral artery topology ( J:239583 )

DMDD

dilated liver sinusoidal space ( J:239583 )

DMDD

abnormal vitelline vein connection ( J:239583 )

DMDD

absent ductus venosus valve ( J:239583 )

DMDD

abnormal coronary sinus connection ( J:239583 )

DMDD

abnormal inferior vena cava valve morphology ( J:239583 )

DMDD

abnormal interatrial septum morphology ( J:239583 )

DMDD

craniofacial

basisphenoid bone foramen ( J:239583 )

DMDD

abnormal viscerocranium morphology ( J:239583 )

DMDD

digestive/alimentary system

decreased parotid gland size ( J:239583 )

DMDD

embryo

abnormal vitelline vein connection ( J:239583 )

DMDD

endocrine/exocrine glands

decreased parotid gland size ( J:239583 )

DMDD

abnormal cystic duct morphology ( J:239583 )

DMDD

dilated bile duct ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

abnormal ovary morphology ( J:239583 )

DMDD

growth/size/body

abnormal viscerocranium morphology ( J:239583 )

DMDD

epididymal cyst ( J:239583 )

DMDD

heterochrony ( J:239583 )

DMDD

homeostasis/metabolism

subcutaneous edema ( J:239583 )

DMDD

immune system

blood in lymph vessels ( J:239583 )

DMDD

integument

subcutaneous edema ( J:239583 )

DMDD

liver/biliary system

dilated liver sinusoidal space ( J:239583 )

DMDD

abnormal cystic duct morphology ( J:239583 )

DMDD

dilated bile duct ( J:239583 )

DMDD

muscle

abnormal eye muscle morphology ( J:239583 )

DMDD

neoplasm

embryo tumor ( J:239583 )

DMDD

nervous system

small superior cervical ganglion ( J:239583 )

DMDD

abnormal forebrain morphology ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

abnormal third ventricle morphology ( J:239583 )

DMDD

exencephaly ( J:239583 )

DMDD

normal phenotype

no abnormal phenotype detected ( J:239583 )

DMDD

reproductive system

abnormal ovary morphology ( J:239583 )

DMDD

epididymal cyst ( J:239583 )

DMDD

skeleton

basisphenoid bone foramen ( J:239583 )

DMDD

abnormal viscerocranium morphology ( J:239583 )

DMDD

abnormal cervical rib ( J:239583 )

DMDD

vision/eye

abnormal eye muscle morphology ( J:239583 )

DMDD

Genotype
MGI:6771964

ht2

• Allelic Composition: Coro1c^{tm1a(KOMP)Wtsi}/Coro1c⁺
• Genetic Background: C57BL/6N-Coro1c^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0343_2_A06

Data Sources

IMPC Data for Coro1c

hematopoietic system

increased erythrocyte cell number ( J:211773 )

IMPC - WTSI

decreased mean corpuscular hemoglobin ( J:211773 )

IMPC - WTSI