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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(DBH-cre)1Cse
transgene insertion 1, Peter Cserjesi
MGI:4417960
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Hand2tm1Cse/Hand2+
Tg(DBH-cre)1Cse/0 		involves: 129S1/Sv MGI:4417973


Genotype
MGI:4417973
cn1
Allelic
Composition		 Hand2tm1Cse/Hand2+
Tg(DBH-cre)1Cse/0
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hand2tm1Cse mutation (0 available); any Hand2 mutation (14 available)
Tg(DBH-cre)1Cse mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:155265 )
• no viable embryos are recovered past 12.5 dpc

cardiovascular system
visceral vascular congestion ( J:155265 )
• all embryos collected at 12.5 dpc exhibit pooling of blood in the liver and peripheral vasculature

liver/biliary system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory