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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lyg1tm1(KOMP)Vlcg
targeted mutation 1, Velocigene
MGI:4415415
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lyg1tm1(KOMP)Vlcg/Lyg1tm1(KOMP)Vlcg involves: C57BL/6NTac MGI:6357195


Genotype
MGI:6357195
hm1
Allelic
Composition		 Lyg1tm1(KOMP)Vlcg/Lyg1tm1(KOMP)Vlcg
Genetic
Background		 involves: C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyg1tm1(KOMP)Vlcg mutation (0 available); any Lyg1 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased tumor growth/size ( J:256594 )
• accelerated tumor growth in a B16 melanoma and a LLC-1 graft model

hematopoietic system

immune system
decreased interferon-gamma secretion ( J:256594 )
• decreased production/secretion by T cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory