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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Prnp-cre/ERT)28.8Ics
transgene insertion 28.8, Mouse Clinical Institute
MGI:4415180
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ate1tm1Avar/Ate1tm2.1Avar
Tg(Prnp-cre/ERT)28.8Ics/0 		involves: 129S1/Sv * C57BL/6 * CBA * SJL MGI:4415720


Genotype
MGI:4415720
cn1
Allelic
Composition		 Ate1tm1Avar/Ate1tm2.1Avar
Tg(Prnp-cre/ERT)28.8Ics/0
Genetic
Background		 involves: 129S1/Sv * C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ate1tm1Avar mutation (0 available); any Ate1 mutation (43 available)
Ate1tm2.1Avar mutation (0 available); any Ate1 mutation (43 available)
Tg(Prnp-cre/ERT)28.8Ics mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reduced male fertility ( J:155421 )
• 33% fewer litters and 50% fewer pups are produced
• matings start from1 month following tamoxifen treatment




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory