All Phenotypes Plec/Parp10<tm1.1Gwi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Plec/Parp10^tm1.1Gwi
targeted mutation 1.1, Gerhard Wiche
MGI:4414773

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plec/Parp10^tm1.1Gwi/Plec/Parp10^tm1.1Gwi	involves: BALB/cJ * C57BL/6	MGI:4414790

Allelic Composition	Plec/Parp10^tm1.1Gwi/Plec/Parp10^tm1.1Gwi
Genetic Background	involves: BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plec/Parp10^tm1.1Gwi mutation (0 available); any Plec mutation (173 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal axon morphology ( J:155511 )

• the number of small myelinated axons in the phrenic nerves is increased compared to in wild-type mice

decreased nerve conduction velocity ( J:155511 )

• in the sciatic nerve

behavior/neurological

behavior/neurological phenotype ( J:155511 )

N	• despite reduced nerve conduction, mice exhibit normal reflexes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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