All Phenotypes Tg(tetO-Gsx2,-EGFP)1Kc MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(tetO-Gsx2,-EGFP)1Kc
transgene insertion 1, Kenneth Campbell
MGI:4412069

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Foxg1^tm1(tTA)Lai/Foxg1⁺ Tg(tetO-Gsx2,-EGFP)1Kc/0	involves: 129S1/Sv	MGI:4412090

Allelic Composition	Foxg1^tm1(tTA)Lai/Foxg1⁺ Tg(tetO-Gsx2,-EGFP)1Kc/0
Genetic Background	involves: 129S1/Sv

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1^tm1(tTA)Lai mutation (0 available); any Foxg1 mutation (28 available)
Tg(tetO-Gsx2,-EGFP)1Kc mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal brain morphology ( J:154936 )

• mice exhibit abnormal brain morphology during embryogenesis that is severe after E15.5

• however, doxycycline-treated mice exhibit improved brain morphology

abnormal telencephalon development ( J:154936 )

• mice exhibit an increase in the expression of ventral telencephalic markers throughout the pallium compared with Tg(tetO-Gsx2,-EGFP)1Kcam mice

abnormal olfactory bulb morphology ( J:154936 )

abnormal lateral ganglionic eminence morphology ( J:154936 )

• after E13.5, mice exposed to doxycycline between E7 and E9 exhibit expansion of the dorsal lateral ganglionic eminence, as determined by marker expression, compared with Tg(tetO-Gsx2,-EGFP)1Kcam mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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