Analysis Tools
cardiovascular system
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• at P0, the aortic laminae is disrupted unlike in wild-type mice
• at P14, the elastic laminae is disrupted unlike in wild-type mice
• at 12 weeks, aorta are less distensible than in wild-type mice
• mice loss the internal elastic lamina in the ascending aorta unlike wild-type mice
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• slightly elongated
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• severe ascending aortic aneurysms
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• the ascending aorta from the aortic root to just distal to the branching point of the brachiocephalic artery is dilated
• however, no aortic stenosis is observed
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• at 12 weeks, aorta are less distensible and stiffer than in wild-type mice
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growth/size/body
muscle
