Phenotypes associated with this allele

• Allele Symbol: Ldah^{tm1(KOMP)Vlcg}
• Allele Name: targeted mutation 1, Velocigene
• Allele ID: MGI:4399711
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ldah^tm1(KOMP)Vlcg/Ldah^tm1(KOMP)Vlcg	involves: C57BL/6J * C57BL/6NTac	MGI:5896411

Genotype
MGI:5896411

hm1

• Allelic Composition: Ldah^{tm1(KOMP)Vlcg}/Ldah^{tm1(KOMP)Vlcg}
• Genetic Background: involves: C57BL/6J * C57BL/6NTac
• Cell Lines: 14003A-H3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:237921 )

• mice are viable and overtly normal with no apparent changes in tissue morphology, body mass, body composition, whole-body energy metabolism, glucose tolerance, or tissue lipid composition whether fed a chow or a high-fat diet

• cholesterol ester (CE) storage and turnover are unaffected in bone marrow-derived macrophages and no changes in CE hydrolase activity or triacylglycerol esterase activity are noted in white adipose tissue (WAT) or liver lysates relative to wild-type controls

• no signs of prostate neoplasia or cancer are observed up to 1 year of age