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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Atf5tm1(KOMP)Vlcg
targeted mutation 1, Velocigene
MGI:4399238
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Atf5tm1(KOMP)Vlcg/Atf5tm1(KOMP)Vlcg involves: C57BL/6NTac MGI:5559543
cn2
Atf5tm1(KOMP)Vlcg/Atf5tm1(KOMP)Vlcg
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Or4e5tm1(cre)Rax/Or4e5+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6NCr * C57BL/6NTac MGI:5559544


Genotype
MGI:5559543
hm1
Allelic
Composition
Atf5tm1(KOMP)Vlcg/Atf5tm1(KOMP)Vlcg
Genetic
Background
involves: C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atf5tm1(KOMP)Vlcg mutation (1 available); any Atf5 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• a small number of mice survival to adulthood

taste/olfaction
• dramatic loss of mature olfactory sensory neurons at P0 and in adult mice

nervous system
• dramatic loss of mature olfactory sensory neurons at P0 and in adult mice

craniofacial
• dramatic loss of mature olfactory sensory neurons at P0 and in adult mice

respiratory system
• dramatic loss of mature olfactory sensory neurons at P0 and in adult mice

growth/size/body
• dramatic loss of mature olfactory sensory neurons at P0 and in adult mice




Genotype
MGI:5559544
cn2
Allelic
Composition
Atf5tm1(KOMP)Vlcg/Atf5tm1(KOMP)Vlcg
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Or4e5tm1(cre)Rax/Or4e5+
Genetic
Background
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6NCr * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atf5tm1(KOMP)Vlcg mutation (1 available); any Atf5 mutation (21 available)
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze mutation (4 available); any Gt(ROSA)26Sor mutation (942 available)
Or4e5tm1(cre)Rax mutation (0 available); any Or4e5 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
taste/olfaction
• frequent olfactory receptor switching at 6 weeks

nervous system
• frequent olfactory receptor switching at 6 weeks

craniofacial
• frequent olfactory receptor switching at 6 weeks

respiratory system
• frequent olfactory receptor switching at 6 weeks

growth/size/body
• frequent olfactory receptor switching at 6 weeks





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory