Phenotypes associated with this allele

• Allele Symbol: Gpr17^tm1Qrlu
• Allele Name: targeted mutation 1, Q Richard Lu
• Allele ID: MGI:4399154
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gpr17^tm1Qrlu/Gpr17^tm1Qrlu	involves: 129S6/SvEvTac * C57BL/6	MGI:4399727

Genotype
MGI:4399727

hm1

• Allelic Composition: Gpr17^tm1Qrlu/Gpr17^tm1Qrlu
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal oligodendrocyte morphology ( J:154602 )

• in culture, oligodendroglial progenitor cells mature earlier than similarly treated wild-type cells

abnormal myelination ( J:154602 )

• at P3, mice exhibit an increase in the number of myelinated axons compared to in wild-type mice

• myelination in the central nervous system occurs earlier than in wild-type mice

• however, adult mice exhibit a normal number of myelinated axons

behavior/neurological

behavior/neurological phenotype ( J:154602 )

N • mice exhibit normal motor skills and behaviors