Phenotypes associated with this allele

• Allele Symbol: Sipa1l3^{Gt(EUCE0020a11)Hmgu}
• Allele Name: gene trap EUCE0020a11, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:4392730
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sipa1l3^Gt(EUCE0020a11)Hmgu/Sipa1l3^Gt(EUCE0020a11)Hmgu	involves: 129P2/OlaHsd * C57BL/6	MGI:5804138

Genotype
MGI:5804138

hm1

• Allelic Composition: Sipa1l3^{Gt(EUCE0020a11)Hmgu}/Sipa1l3^{Gt(EUCE0020a11)Hmgu}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

posterior iris synechia ( J:226326 )

• some mice exhibit lenticular-iridial adhesions

abnormal lens morphology ( J:226326 )

• flattened appearance with lack of distinctive equatorial zone, vacuoles between anterior lens epithelial cells and adjacent posterior lens fibers, and abnormal cell clusters in the region of the expected germinative zone

• however, E14.5 lenses have no additional cells

abnormal lens epithelium morphology ( J:226326 )

• extra cells in the anterior lens epithelium

abnormal lens fiber morphology ( J:226326 )

• undulated lens fiber cells at E18.5

• vacuoles and proteinaceous aggregates in fiber cells

cataract ( J:226326 )

small lens ( J:226326 )

• at 4 weeks

microphthalmia ( J:226326 )

• at 4 weeks