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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Thy1-EGFP)SJrs
transgene insertion S, Joshua R Sanes
MGI:4367719
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Nrn1tm1.2Ndiv/Nrn1tm1.2Ndiv
Tg(Thy1-EGFP)SJrs/0 		involves: C57BL/6 * CBA MGI:5307920


Genotype
MGI:5307920
cx1
Allelic
Composition		 Nrn1tm1.2Ndiv/Nrn1tm1.2Ndiv
Tg(Thy1-EGFP)SJrs/0
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrn1tm1.2Ndiv mutation (1 available); any Nrn1 mutation (18 available)
Tg(Thy1-EGFP)SJrs mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal CNS synapse formation ( J:178970 )
• the percentage of dynamic events (spine gain or loss from neocortical neurons) that persist are significantly higher compared to wild-type mice
• the percentage of dynamic-persistent events that favor spine loss relative to dynamic-persistent events that favor spine gain is increased compared to wild-type controls suggesting a decrease in spine stabilization




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory