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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pkd1tm2.1Bol
targeted mutation 2.1, Alessandra Boletta
MGI:4366012
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pkd1tm2.1Bol/Pkd1tm2.1Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac MGI:4366023
ht2
 		Pkd1tm2.1Bol/Pkd1tm2.2Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac MGI:4366021
ht3
 		Pkd1tm2.1Bol/Pkd1tm3.2Bol involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac MGI:4366022


Genotype
MGI:4366023
hm1
Allelic
Composition		 Pkd1tm2.1Bol/Pkd1tm2.1Bol
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm2.1Bol mutation (0 available); any Pkd1 mutation (153 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:153606 )
• mice do not develop any renal or extra-renal defects even with aging




Genotype
MGI:4366021
ht2
Allelic
Composition		 Pkd1tm2.1Bol/Pkd1tm2.2Bol
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm2.1Bol mutation (0 available); any Pkd1 mutation (153 available)
Pkd1tm2.2Bol mutation (0 available); any Pkd1 mutation (153 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:153606 )
• mice are viable and fertile and do not develop renal, hepatic, or pancreatic cysts by 18 months of age




Genotype
MGI:4366022
ht3
Allelic
Composition		 Pkd1tm2.1Bol/Pkd1tm3.2Bol
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm2.1Bol mutation (0 available); any Pkd1 mutation (153 available)
Pkd1tm3.2Bol mutation (0 available); any Pkd1 mutation (153 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:153606 )
• mice are viable and fertile and do not develop renal, hepatic, or pancreatic cysts by 18 months of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory