Phenotypes associated with this allele

• Allele Symbol: Hoxc8^tm2Jepl
• Allele Name: targeted mutation 2, Jeh-Ping Liu
• Allele ID: MGI:4365797
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hoxc8^tm2Jepl/Hoxc8^tm2Jepl	involves: 129S1/Sv * C57BL/6	MGI:4365816
ht2	Hoxc8^tm2Jepl/Hoxc8^+	involves: 129S1/Sv * C57BL/6	MGI:4365817

Genotype
MGI:4365816

hm1

• Allelic Composition: Hoxc8^tm2Jepl/Hoxc8^tm2Jepl
• Genetic Background: involves: 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal sternocostal joint morphology ( J:153560 )

• unlike in wild-type mice, the eighth ribs attach to the sternum

increased rib number ( J:153560 )

• mice have extra ribs extending from C7 unlike wild-type mice

cervical vertebral transformation ( J:153560 )

• mice have extra ribs extending from C7 unlike wild-type mice

behavior/neurological

behavior/neurological phenotype ( J:153560 )

N • mice exhibit normal grip strength

Genotype
MGI:4365817

ht2

• Allelic Composition: Hoxc8^tm2Jepl/Hoxc8⁺
• Genetic Background: involves: 129S1/Sv * C57BL/6

skeleton

abnormal sternocostal joint morphology ( J:153560 )

• unlike in wild-type mice, one of the eighth ribs in some mice attach to the sternum

increased rib number ( J:153560 )

• some mice have extra partial ribs extending from C7 unlike wild-type mice

cervical vertebral transformation ( J:153560 )

• mice have extra ribs extending from C7 unlike wild-type mice