Phenotypes associated with this allele

• Allele Symbol: Mybphl^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4364468
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mybphl^tm1a(KOMP)Wtsi/Mybphl^tm1a(KOMP)Wtsi	C57BL/6N-Mybphl^tm1a(KOMP)Wtsi/Wtsi	MGI:5631325

Genotype
MGI:5631325

hm1

• Allelic Composition: Mybphl^{tm1a(KOMP)Wtsi}/Mybphl^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Mybphl^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0108_2_C06

Data Sources

IMPC Data for Mybphl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased grip strength ( J:211773 )

IMPC - WTSI

cardiovascular system

abnormal vertebral artery topology ( J:239583 )

DMDD

hemorrhage ( J:239583 )

DMDD

immune system

blood in lymph vessels ( J:239583 )

DMDD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

muscle

abnormal eye muscle morphology ( J:239583 )

DMDD

nervous system

abnormal forebrain morphology ( J:239583 )

DMDD

abnormal optic chiasm morphology ( J:239583 )

DMDD

skeleton

fusion of vertebral arches ( J:239583 )

DMDD

vision/eye

abnormal eye muscle morphology ( J:239583 )

DMDD

abnormal optic chiasm morphology ( J:239583 )

DMDD

abnormal lens morphology ( J:239583 )

DMDD

aphakia ( J:239583 )

DMDD

abnormal optic cup morphology ( J:239583 )

DMDD

abnormal optic stalk morphology ( J:239583 )

DMDD