Phenotypes associated with this allele

• Allele Symbol: Trim45^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4363243
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trim45^tm1a(KOMP)Wtsi/Trim45^tm1a(KOMP)Wtsi	B6Brd;B6Dnk;B6N-Trim45^tm1a(KOMP)Wtsi Tyr^c-Brd/Wtsi	MGI:5883887

Genotype
MGI:5883887

hm1

• Allelic Composition: Trim45^{tm1a(KOMP)Wtsi}/Trim45^{tm1a(KOMP)Wtsi}
• Genetic Background: B6Brd;B6Dnk;B6N-Trim45^{tm1a(KOMP)Wtsi} Tyr^c-Brd/Wtsi
• Cell Lines: EPD0056_1_B09

Data Sources

IMPC Data for Trim45

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

absent segment of posterior cerebral artery ( J:239583 )

DMDD

abnormal vertebral artery topology ( J:239583 )

DMDD

additional anastomosis between intracranial vertebral arteries ( J:239583 )

DMDD

abnormal vitelline vein connection ( J:239583 )

DMDD

abnormal ductus venosus valve morphology ( J:239583 )

DMDD

abnormal inferior vena cava morphology ( J:239583 )

DMDD

abnormal interatrial septum morphology ( J:239583 )

DMDD

bicuspid aortic valve ( J:239583 )

DMDD

embryo

abnormal vitelline vein connection ( J:239583 )

DMDD

abnormal Wolffian duct morphology ( J:239583 )

DMDD

homeostasis/metabolism

subcutaneous edema ( J:239583 )

DMDD

immune system

blood in lymph vessels ( J:239583 )

DMDD

integument

subcutaneous edema ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

nervous system

absent segment of posterior cerebral artery ( J:239583 )

DMDD

abnormal forebrain morphology ( J:239583 )

DMDD

skeleton

fusion of vertebral arches ( J:239583 )

DMDD

vision/eye

aphakia ( J:239583 )

DMDD

abnormal optic cup morphology ( J:239583 )

DMDD