Phenotypes associated with this allele

• Allele Symbol: Ap4e1^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4362509
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ap4e1^tm1a(KOMP)Wtsi/Ap4e1^tm1a(KOMP)Wtsi	C57BL/6N-Ap4e1^tm1a(KOMP)Wtsi/Wtsi	MGI:5781568
hm2	Ap4e1^tm1a(KOMP)Wtsi/Ap4e1^tm1a(KOMP)Wtsi	involves: C57BL/6N	MGI:5544015

Genotype
MGI:5781568

hm1

• Allelic Composition: Ap4e1^{tm1a(KOMP)Wtsi}/Ap4e1^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Ap4e1^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0025_5_A08

Data Sources

IMPC Data for Ap4e1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:175295 )

IMPC - WTSI

growth/size/body

increased lean body mass ( J:175295 )

♂

IMPC - WTSI

hematopoietic system

decreased hemoglobin content ( J:175295 )

IMPC - WTSI

decreased mean corpuscular hemoglobin ( J:175295 )

IMPC - WTSI

limbs/digits/tail

abnormal femur morphology ( J:175295 )

♂

IMPC - WTSI

skeleton

abnormal femur morphology ( J:175295 )

♂

IMPC - WTSI

increased bone mineral density ( J:175295 )

♂

IMPC - WTSI

Genotype
MGI:5544015

hm2

• Allelic Composition: Ap4e1^{tm1a(KOMP)Wtsi}/Ap4e1^{tm1a(KOMP)Wtsi}
• Genetic Background: involves: C57BL/6N
• Cell Lines: EPD0025_5_A08

nervous system

enlarged lateral ventricles ( J:200082 )

• increased area

decreased corpus callosum size ( J:200082 )

• decreased span

behavior/neurological

decreased vertical activity ( J:200082 )

hematopoietic system

anemia ( J:200082 )

♀ • in female mice