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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nanos3tm2.1(cre)Ysa
targeted mutation 2.1, Yumiko Saga
MGI:4358405
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Dnaaf11tm1.1Hmd/Dnaaf11tm1.1Hmd
Nanos3tm2.1(cre)Ysa/Nanos3+ 		involves: 129S6/SvEvTac * C57BL/6NCrlj * CBA/JNCrlj MGI:6285736
cn2
 		Nanos3tm2.1(cre)Ysa/Nanos3+
Pofut1tm1Ysa/Pofut1tm1.1Ysa 		involves: C3H/HeNJcl * C57BL/6NCrlj * C57BL/6NJcl * CBA/JNCrlj MGI:5426709


Genotype
MGI:6285736
cn1
Allelic
Composition		 Dnaaf11tm1.1Hmd/Dnaaf11tm1.1Hmd
Nanos3tm2.1(cre)Ysa/Nanos3+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NCrlj * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnaaf11tm1.1Hmd mutation (0 available); any Dnaaf11 mutation (26 available)
Nanos3tm2.1(cre)Ysa mutation (1 available); any Nanos3 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
immotile sperm ( J:258369 )
• sperm were completely immotile

cellular
immotile sperm ( J:258369 )
• sperm were completely immotile




Genotype
MGI:5426709
cn2
Allelic
Composition		 Nanos3tm2.1(cre)Ysa/Nanos3+
Pofut1tm1Ysa/Pofut1tm1.1Ysa
Genetic
Background		 involves: C3H/HeNJcl * C57BL/6NCrlj * C57BL/6NJcl * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nanos3tm2.1(cre)Ysa mutation (1 available); any Nanos3 mutation (28 available)
Pofut1tm1.1Ysa mutation (0 available); any Pofut1 mutation (22 available)
Pofut1tm1Ysa mutation (0 available); any Pofut1 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:183324 )
N
• in 8-week old males, external morphology of the testes, histology of seminiferous tubules, and number of sperm in epididymides are normal; when bred to wild-type females, fecundity is similar to controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory