Phenotypes associated with this allele

• Allele Symbol: Tln2^tm2Crit
• Allele Name: targeted mutation 2, David R Critchley
• Allele ID: MGI:4358373
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tln2^tm2Crit/Tln2^tm2Crit	involves: 129P2/OlaHsd * C57BL/6	MGI:4946297

Genotype
MGI:4946297

hm1

• Allelic Composition: Tln2^tm2Crit/Tln2^tm2Crit
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

centrally nucleated skeletal muscle fibers ( J:190037 )

• at 5 months

dystrophic muscle ( J:190037 )

• mild at 5 months

cellular

cellular phenotype ( J:190037 )

N • mouse embryonic fibroblasts exhibit normal cell spreading and wound closure

decreased fibroblast proliferation ( J:190037 )

• slightly reduced in mouse embryonic fibroblasts