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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Stk4tm1.1Wtao
targeted mutation 1.1, Wufan Tao
MGI:4358199
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Stk4tm1.1Wtao/Stk4tm1.2Wtao
Tg(Lck-cre)#Zhu/0 		involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL/J MGI:4358230


Genotype
MGI:4358230
cn1
Allelic
Composition		 Stk4tm1.1Wtao/Stk4tm1.2Wtao
Tg(Lck-cre)#Zhu/0
Genetic
Background		 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stk4tm1.1Wtao mutation (0 available); any Stk4 mutation (75 available)
Stk4tm1.2Wtao mutation (0 available); any Stk4 mutation (75 available)
Tg(Lck-cre)#Zhu mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased T cell number ( J:152323 )
• peripheral T cells
decreased CD4-positive, alpha-beta T cell number ( J:152323 )
• in the blood, spleen, and lymph nodes
decreased CD8-positive, alpha-beta T cell number ( J:152323 )
• in the blood, spleen, and lymph nodes

hematopoietic system
decreased T cell number ( J:152323 )
• peripheral T cells
decreased CD4-positive, alpha-beta T cell number ( J:152323 )
• in the blood, spleen, and lymph nodes
decreased CD8-positive, alpha-beta T cell number ( J:152323 )
• in the blood, spleen, and lymph nodes

endocrine/exocrine glands




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory