All Phenotypes Crtc2<tm1.1Khk> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Crtc2^tm1.1Khk
targeted mutation 1.1, Klaus H Kaestner
MGI:4355660

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Crtc2^tm1.1Khk/Crtc2^tm1.1Khk	involves: C57BL/6 * C57BL/6J * FVB/N	MGI:4355662

Allelic Composition	Crtc2^tm1.1Khk/Crtc2^tm1.1Khk
Genetic Background	involves: C57BL/6 * C57BL/6J * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crtc2^tm1.1Khk mutation (0 available); any Crtc2 mutation (29 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

• small

abnormal glucose homeostasis ( J:151618 )

• following glucagon stimulation, isolated hepatocytes exhibit reduced glucose secretion compared with similarly treated wild-type cells

decreased glycogen level ( J:151618 )

• in liver and muscle cells of fed mice

liver/biliary system

abnormal liver physiology ( J:151618 )

• following glucagon stimulation, isolated hepatocytes exhibit reduced glucose secretion compared with similarly treated wild-type cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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