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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Afdntm2Ytk
targeted mutation 2, Yoshimi Takai
MGI:4354298
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Afdntm2Ytk/Afdntm2Ytk
Tg(Camk2a-cre)1Gsc/0 		involves: FVB/N MGI:4354299


Genotype
MGI:4354299
cn1
Allelic
Composition		 Afdntm2Ytk/Afdntm2Ytk
Tg(Camk2a-cre)1Gsc/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Afdntm2Ytk mutation (0 available); any Afdn mutation (84 available)
Tg(Camk2a-cre)1Gsc mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal synapse morphology ( J:151436 )
• the number of puncta adherentia junctions per bouton is decreased compared to in wild-type mice
• the number of perforated synapses is increased compared to in wild-type mice
• however, the number of postsynaptic densities per bouton is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory