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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itga4tm1Leg
targeted mutation 1, Lawrence E Goldfinger
MGI:4354168
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itga4tm1Leg/Itga4tm1Leg Not Specified MGI:4354171


Genotype
MGI:4354171
hm1
Allelic
Composition		 Itga4tm1Leg/Itga4tm1Leg
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itga4tm1Leg mutation (0 available); any Itga4 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell physiology ( J:151371 )
• pulmonary endothelial cells subjected invitro to laminar shear stress for 20 hours fail to align normally in the flow direction




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory