About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Szt2Gt(XH662)Byg
gene trap XH662, BayGenomics
MGI:4353996
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Szt2Gt(XH662)Byg/Szt2Gt(XH662)Byg (B6.129P2-Szt2Gt(XH662)Byg x 129S1.129P2-Szt2Gt(XH662)Byg)F1 MGI:4354000
hm2
 		Szt2Gt(XH662)Byg/Szt2Gt(XH662)Byg 129S1.129P2(B6)-Szt2Gt(XH662)Byg/FrkJ MGI:4353999
hm3
 		Szt2Gt(XH662)Byg/Szt2Gt(XH662)Byg B6.129P2-Szt2Gt(XH662)Byg/FrkJ MGI:4354002
ht4
 		Szt2Gt(XH662)Byg/Szt2+ involves: 129P2/OlaHsd * C57BL/6J MGI:4356430
ht5
 		Szt2Gt(XH662)Byg/Szt2m1Frk involves: 129P2/OlaHsd * C57BL/6J MGI:4354001


Genotype
MGI:4354000
hm1
Allelic
Composition		 Szt2Gt(XH662)Byg/Szt2Gt(XH662)Byg
Genetic
Background		 (B6.129P2-Szt2Gt(XH662)Byg x 129S1.129P2-Szt2Gt(XH662)Byg)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Szt2Gt(XH662)Byg mutation (2 available); any Szt2 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:150942 )
• when examined at weaning only about 10% of the expected number of homozygotes are found




Genotype
MGI:4353999
hm2
Allelic
Composition		 Szt2Gt(XH662)Byg/Szt2Gt(XH662)Byg
Genetic
Background		 129S1.129P2(B6)-Szt2Gt(XH662)Byg/FrkJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Szt2Gt(XH662)Byg mutation (2 available); any Szt2 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased survivor rate ( J:150942 )
• when examined at weaning only about 10% of the expected number of homozygotes are found
preweaning lethality, incomplete penetrance ( J:150942 )
• when examined at weaning only about 10% of the expected number of homozygotes are found

behavior/neurological
maximal tonic hindlimb extension seizures ( J:150942 )
• several mice went past the minimal clonic seizure endpoint proceeding directly to tonic hindlimb extension
minimal clonic seizures ( J:150942 )
• increased sensitivity to electrically induced minimal clonic seizures

pigmentation
diluted coat color ( J:150942 )
• slightly diluted coat color

nervous system
maximal tonic hindlimb extension seizures ( J:150942 )
• several mice went past the minimal clonic seizure endpoint proceeding directly to tonic hindlimb extension
minimal clonic seizures ( J:150942 )
• increased sensitivity to electrically induced minimal clonic seizures

integument
diluted coat color ( J:150942 )
• slightly diluted coat color




Genotype
MGI:4354002
hm3
Allelic
Composition		 Szt2Gt(XH662)Byg/Szt2Gt(XH662)Byg
Genetic
Background		 B6.129P2-Szt2Gt(XH662)Byg/FrkJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Szt2Gt(XH662)Byg mutation (2 available); any Szt2 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:150942 )
• no homozygotes are detected at weaning




Genotype
MGI:4356430
ht4
Allelic
Composition		 Szt2Gt(XH662)Byg/Szt2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Szt2Gt(XH662)Byg mutation (2 available); any Szt2 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
minimal clonic seizures ( J:150942 )
• slight increase in the incidence of electrically induced seizures compared to controls

nervous system
minimal clonic seizures ( J:150942 )
• slight increase in the incidence of electrically induced seizures compared to controls




Genotype
MGI:4354001
ht5
Allelic
Composition		 Szt2Gt(XH662)Byg/Szt2m1Frk
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Szt2Gt(XH662)Byg mutation (2 available); any Szt2 mutation (94 available)
Szt2m1Frk mutation (2 available); any Szt2 mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
minimal clonic seizures ( J:150942 )
• increased incidence of electrically induced seizures compared to controls

nervous system
minimal clonic seizures ( J:150942 )
• increased incidence of electrically induced seizures compared to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory