Phenotypes associated with this allele

• Allele Symbol: Cdk5rap2^{Gt(RRU031)Byg}
• Allele Name: gene trap RRU031, BayGenomics
• Allele ID: MGI:4338479
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdk5rap2^Gt(RRU031)Byg/Cdk5rap2^Gt(RRU031)Byg	involves: 129P2/OlaHsd * C57BL/6J	MGI:4830309

Genotype
MGI:4830309

hm1

• Allelic Composition: Cdk5rap2^{Gt(RRU031)Byg}/Cdk5rap2^{Gt(RRU031)Byg}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

cellular phenotype ( J:163849 )

N • mouse embryonic fibroblasts exhibit normal centriole numbers

abnormal centrosome morphology ( J:163849 )

• centrosomes are disrupted in mouse embryonic fibroblasts compared to in wild-type cells

abnormal pericentriolar material morphology ( J:163849 )

• mouse embryonic fibroblasts exhibit a decrease in strong pericentriolar material (PCM) fibers and an increase in weak PCM fibers compared with wild-type cells