Phenotypes associated with this allele

• Allele Symbol: Rif1^{Gt(A045A01)Wrst}
• Allele Name: gene trap A045A01, German Gene Trap Consortium
• Allele ID: MGI:4335499
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rif1^Gt(A045A01)Wrst/Rif1^Gt(A045A01)Wrst	involves: 129S2/SvPas * C57BL/6J	MGI:4417939

Genotype
MGI:4417939

hm1

• Allelic Composition: Rif1^{Gt(A045A01)Wrst}/Rif1^{Gt(A045A01)Wrst}
• Genetic Background: involves: 129S2/SvPas * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:155449 )

• fewer than expected mice are observed at weaning

embryonic lethality during organogenesis, incomplete penetrance ( J:155449 )

• fewer than expected mice are observed at E12.5

reproductive system

reduced fertility ( J:155449 )

cellular

abnormal mitosis ( J:155449 )

• mouse embryonic fibroblasts progress slower through S phase than wild-type cells

decreased cell proliferation ( J:155449 )

• mouse embryonic fibroblasts exhibit decreased proliferation compared with wild-type cells

growth/size/body

postnatal growth retardation ( J:155449 )

• slightly