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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Klf8Gt(AD0101)Wtsi
gene trap AD0101, Wellcome Trust Sanger Institute
MGI:4331301
Summary 6 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Klf8Gt(AD0101)Wtsi/Klf8Gt(AD0101)Wtsi FVB.129P2-Klf8Gt(AD0101)Wtsi/Apb MGI:5538298
ht2
Klf8Gt(AD0101)Wtsi/Klf8+ FVB.129P2-Klf8Gt(AD0101)Wtsi/Apb MGI:5538302
cx3
Klf3tm1Merc/Klf3tm1Merc
Klf8Gt(AD0101)Wtsi/Klf8Gt(AD0101)Wtsi
involves: 129P2/OlaHsd * FVB/NJ MGI:5538300
cx4
Klf3tm1Merc/Klf3tm1Merc
Klf8Gt(AD0101)Wtsi/Klf8+
involves: 129P2/OlaHsd * FVB/NJ MGI:5538301
cx5
Klf3tm1Merc/Klf3tm1Merc
Klf8Gt(AD0101)Wtsi/Y
involves: 129P2/OlaHsd * FVB/NJ MGI:5538303
ot6
Klf8Gt(AD0101)Wtsi/Y FVB.129P2-Klf8Gt(AD0101)Wtsi/Apb MGI:5538297


Genotype
MGI:5538298
hm1
Allelic
Composition
Klf8Gt(AD0101)Wtsi/Klf8Gt(AD0101)Wtsi
Genetic
Background
FVB.129P2-Klf8Gt(AD0101)Wtsi/Apb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klf8Gt(AD0101)Wtsi mutation (1 available); any Klf8 mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• some mice by 6 months

hematopoietic system
N
• mice exhibit normal full blood counts indicating normal erythroid parameters and platelet numbers and normal response to phenylhydrazine treatment




Genotype
MGI:5538302
ht2
Allelic
Composition
Klf8Gt(AD0101)Wtsi/Klf8+
Genetic
Background
FVB.129P2-Klf8Gt(AD0101)Wtsi/Apb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klf8Gt(AD0101)Wtsi mutation (1 available); any Klf8 mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• some mice by 6 months




Genotype
MGI:5538300
cx3
Allelic
Composition
Klf3tm1Merc/Klf3tm1Merc
Klf8Gt(AD0101)Wtsi/Klf8Gt(AD0101)Wtsi
Genetic
Background
involves: 129P2/OlaHsd * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klf3tm1Merc mutation (2 available); any Klf3 mutation (80 available)
Klf8Gt(AD0101)Wtsi mutation (1 available); any Klf8 mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most mice die between E12.5 and E14.5

embryo
N
• mice are largely normal at E13.5




Genotype
MGI:5538301
cx4
Allelic
Composition
Klf3tm1Merc/Klf3tm1Merc
Klf8Gt(AD0101)Wtsi/Klf8+
Genetic
Background
involves: 129P2/OlaHsd * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klf3tm1Merc mutation (2 available); any Klf3 mutation (80 available)
Klf8Gt(AD0101)Wtsi mutation (1 available); any Klf8 mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected mice are present at weaning




Genotype
MGI:5538303
cx5
Allelic
Composition
Klf3tm1Merc/Klf3tm1Merc
Klf8Gt(AD0101)Wtsi/Y
Genetic
Background
involves: 129P2/OlaHsd * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klf3tm1Merc mutation (2 available); any Klf3 mutation (80 available)
Klf8Gt(AD0101)Wtsi mutation (1 available); any Klf8 mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most mice die between E12.5 and E14.5

embryo
N
• mice are largely normal at E13.5




Genotype
MGI:5538297
ot6
Allelic
Composition
Klf8Gt(AD0101)Wtsi/Y
Genetic
Background
FVB.129P2-Klf8Gt(AD0101)Wtsi/Apb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klf8Gt(AD0101)Wtsi mutation (1 available); any Klf8 mutation (67 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• some mice by 6 months

hematopoietic system
N
• mice exhibit normal full blood counts indicating normal erythroid parameters and platelet numbers and normal response to phenylhydrazine treatment





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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory