Phenotypes associated with this allele

• Allele Symbol: Tut4^{Gt(RRR277)Byg}
• Allele Name: gene trap RRR277, BayGenomics
• Allele ID: MGI:4330742
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tut4^Gt(RRR277)Byg/Tut4^Gt(RRR277)Byg	B6.129P2-Tut4^Gt(RRR277)Byg	MGI:5491875

Genotype
MGI:5491875

hm1

• Allelic Composition: Tut4^{Gt(RRR277)Byg}/Tut4^{Gt(RRR277)Byg}
• Genetic Background: B6.129P2-Tut4^{Gt(RRR277)Byg}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:194669 )

• 50% of mice die by P8

growth/size/body

decreased body weight ( J:194669 )

postnatal growth retardation ( J:194669 )

• in the first week

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:194669 )

N • growth hormone serum levels are normal

decreased circulating insulin-like growth factor I level ( J:194669 )

cellular

abnormal cell physiology ( J:194669 )

• mature miRNA lengths and terminal uridine frequencies are reduced

• however, quantities of mature miRNA are normal