Phenotypes associated with this allele

• Allele Symbol: Usp22^{Gt(RRS377)Byg}
• Allele Name: gene trap RRS377, BayGenomics
• Allele ID: MGI:4330216
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Usp22^Gt(RRS377)Byg/Usp22^Gt(RRS377)Byg	involves: 129P2/OlaHsd * C57BL/6	MGI:7407156

Genotype
MGI:7407156

hm1

• Allelic Composition: Usp22^{Gt(RRS377)Byg}/Usp22^{Gt(RRS377)Byg}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

hypoxia ( J:272613 )

cardiovascular system

abnormal placental labyrinth vasculature morphology ( J:272613 )

• at E12.5, the network of fetal vessels were dilated and poorly developed

• the number of fetal vessels in the labyrinth of mutant embryos was significantly reduced

embryo

abnormal placental labyrinth vasculature morphology ( J:272613 )

• at E12.5, the network of fetal vessels were dilated and poorly developed

• the number of fetal vessels in the labyrinth of mutant embryos was significantly reduced

abnormal placenta intervillous maternal lacunae morphology ( J:272613 )

• at E12.5, maternal sinuses were dilated and poorly developed

placental labyrinth hypoplasia ( J:272613 )

• at E12.5, the cellular density of the labyrinth epithelium is decreased

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:272613 )

• embryos survived until 11.5-14.5 days postcoitum, but died shortly thereafter