Phenotypes associated with this allele

• Allele Symbol: Tmem231^{Gt(OST335874)Lex}
• Allele Name: gene trap OST335874, Lexicon Genetics
• Allele ID: MGI:4284576
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem231^Gt(OST335874)Lex/Tmem231^Gt(OST335874)Lex	involves: 129S5/SvEvBrd * C57BL/6	MGI:5301844

Genotype
MGI:5301844

hm1

• Allelic Composition: Tmem231^{Gt(OST335874)Lex}/Tmem231^{Gt(OST335874)Lex}
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:178978 )

• die around E15.5

embryo

abnormal embryonic neuroepithelium morphology ( J:178978 )

• striking loss of cilia in the spinal cord neuroectoderm

nervous system

abnormal nervous system development ( J:178978 )

• patterning defects of the ventral spinal cord

abnormal embryonic neuroepithelium morphology ( J:178978 )

• striking loss of cilia in the spinal cord neuroectoderm

cardiovascular system

abnormal blood vessel morphology ( J:178978 )

• severe vascular defects

limbs/digits/tail

polydactyly ( J:178978 )

vision/eye

microphthalmia ( J:178978 )