About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ropn1lGt(OST20298)Lex
gene trap OST20298, Lexicon Genetics
MGI:4143866
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ropn1lGt(OST20298)Lex/Ropn1lGt(OST20298)Lex involves: 129S5/SvEvBrd MGI:5552712
cx2
 		Ropn1Gt(OST21705)Lex/Ropn1Gt(OST21705)Lex
Ropn1lGt(OST20298)Lex/Ropn1lGt(OST20298)Lex 		involves: 129S5/SvEvBrd MGI:5552713


Genotype
MGI:5552712
hm1
Allelic
Composition		 Ropn1lGt(OST20298)Lex/Ropn1lGt(OST20298)Lex
Genetic
Background		 involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ropn1lGt(OST20298)Lex mutation (2 available); any Ropn1l mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:206788 )
N
• mice exhibit normal sperm motility and male fertility

respiratory system
respiratory system phenotype ( J:206788 )
N
• mice exhibit normal respiratory cilia morphology

cellular




Genotype
MGI:5552713
cx2
Allelic
Composition		 Ropn1Gt(OST21705)Lex/Ropn1Gt(OST21705)Lex
Ropn1lGt(OST20298)Lex/Ropn1lGt(OST20298)Lex
Genetic
Background		 involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ropn1Gt(OST21705)Lex mutation (2 available); any Ropn1 mutation (10 available)
Ropn1lGt(OST20298)Lex mutation (2 available); any Ropn1l mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
immotile sperm ( J:206788 )
• completely immotile
male infertility ( J:206788 )
• despite confirmed mating

cellular
immotile sperm ( J:206788 )
• completely immotile

respiratory system
respiratory system phenotype ( J:206788 )
N
• mice exhibit normal respiratory cilia morphology and physiology




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory