Phenotypes associated with this allele

• Allele Symbol: Lin9^{Gt(RRI306)Byg}
• Allele Name: gene trap RRI306, BayGenomics
• Allele ID: MGI:4129434
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lin9^Gt(RRI306)Byg/Lin9^Gt(RRI306)Byg	involves: 129P2/OlaHsd	MGI:4819581

Genotype
MGI:4819581

hm1

• Allelic Composition: Lin9^{Gt(RRI306)Byg}/Lin9^{Gt(RRI306)Byg}
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and placentation, complete penetrance ( J:162678 )

• mice die between E3.5 and E7.5

embryo

absent inner cell mass proliferation ( J:162678 )

• in culture, the inner cell mass fails to expand unlike in wild-type mice

abnormal embryo development ( J:162678 )

• at E6.5, embryos are highly abnormal and do not develop the three germ layers, amnion, chorion, and allantois unlike wild-type mice

absent embryonic epiblast ( J:162678 )

• at E7.5, embryos lack typical epithelial cells of the epiblasts unlike in wild-type mice

inner cell mass degeneration ( J:162678 )

• by 7 days in culture, inner cell mass of most embryos is lost unlike wild-type cells

absent allantois ( J:162678 )

absent amnion ( J:162678 )

absent chorion ( J:162678 )

cellular

absent inner cell mass proliferation ( J:162678 )

• in culture, the inner cell mass fails to expand unlike in wild-type mice