Phenotypes associated with this allele

• Allele Symbol: Traf3ip1^{Gt(RRJ005)Byg}
• Allele Name: gene trap RRJ005, BayGenomics
• Allele ID: MGI:4129326
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Traf3ip1^Gt(RRJ005)Byg/Traf3ip1^Gt(RRJ005)Byg	involves: 129P2/OlaHsd * C57BL/6	MGI:5299347

Genotype
MGI:5299347

hm1

• Allelic Composition: Traf3ip1^{Gt(RRJ005)Byg}/Traf3ip1^{Gt(RRJ005)Byg}
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:178483 )

embryo

absent embryonic cilia ( J:178483 )

• embryonic fibroblasts fail to form cilia in vitro

abnormal neural tube morphology ( J:178483 )

• neural tube patterning abnormalities consistent with defects in cilia

limbs/digits/tail

polydactyly ( J:178483 )

• at E13.5

curly tail ( J:178483 )

• at E10.5

homeostasis/metabolism

cardiac edema ( J:178483 )

• cardiac edema at E13.5

nervous system

abnormal nervous system development ( J:178483 )

• at E10.5

abnormal neural tube morphology ( J:178483 )

• neural tube patterning abnormalities consistent with defects in cilia

vision/eye

microphthalmia ( J:178483 )

• in several mice at E10.5

cellular

absent embryonic cilia ( J:178483 )

• embryonic fibroblasts fail to form cilia in vitro