Phenotypes associated with this allele

• Allele Symbol: Egln1^{Gt(RRG405)Byg}
• Allele Name: gene trap RRG405, BayGenomics
• Allele ID: MGI:4128927
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Egln1^Gt(RRG405)Byg/Egln1^Gt(RRG405)Byg	involves: 129P2/OlaHsd	MGI:4819535
cx2	Egln1^Gt(RRG405)Byg/Egln1^Gt(RRG405)Byg P4htm^tm1Jomy/P4htm^tm1Jomy	Not Specified	MGI:5583848

Genotype
MGI:4819535

hm1

• Allelic Composition: Egln1^{Gt(RRG405)Byg}/Egln1^{Gt(RRG405)Byg}
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:162597 )

N • mice exhibit normal angiogenesis

abnormal heart morphology ( J:162597 )

• the area occupied by mitochondria in the heart is increased compared to in wild-type mice

• however, heart weight is normal

abnormal response of heart to induced stress ( J:162597 )

• following ischemia-reperfusion injury, mice exhibit improved mechanical recovery compared with similarly treated wild-type mice

growth/size/body

decreased body weight ( J:162597 )

hematopoietic system

hematopoietic system phenotype ( J:162597 )

N • mice do not exhibit polycythemia

homeostasis/metabolism

abnormal response of heart to induced stress ( J:162597 )

• following ischemia-reperfusion injury, mice exhibit improved mechanical recovery compared with similarly treated wild-type mice

Genotype
MGI:5583848

cx2

• Allelic Composition: Egln1^{Gt(RRG405)Byg}/Egln1^{Gt(RRG405)Byg}; P4htm^tm1Jomy/P4htm^tm1Jomy
• Genetic Background: Not Specified

hematopoietic system

increased hematocrit ( J:213191 )

increased mean corpuscular hemoglobin concentration ( J:213191 )

homeostasis/metabolism

decreased circulating erythropoietin level ( J:213191 )