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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pdia3Gt(RST613)Byg
gene trap RST613, BayGenomics
MGI:4128251
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Pdia3Gt(RST613)Byg/Pdia3Gt(RST613)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:4837405
ht2
Pdia3Gt(RST613)Byg/Pdia3+ involves: 129P2/OlaHsd * C57BL/6 MGI:4837406


Genotype
MGI:4837405
hm1
Allelic
Composition
Pdia3Gt(RST613)Byg/Pdia3Gt(RST613)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdia3Gt(RST613)Byg mutation (0 available); any Pdia3 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice are not observed after birth




Genotype
MGI:4837406
ht2
Allelic
Composition
Pdia3Gt(RST613)Byg/Pdia3+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdia3Gt(RST613)Byg mutation (0 available); any Pdia3 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• at 15 weeks, mice exhibit decreased cortical bone area compared with wild-type mice
• however, cortical bone thickness is normal
• at 15 weeks, trabecular space in the distal femoral metaphysis is decreased compared to in wild-type mice
• however, trabecular thickness is normal in the distal femoral metaphysis and trabecular bone in the distal femoral epiphysis is normal
• at 15 weeks, mice exhibit increased bone volume to trabecular volume in the distal femoral metaphysis compared with wild-type mice
• at 15 weeks, mice exhibit increased trabecular number compared with wild-type mice





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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory