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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dusp4Gt(XG164)Byg
gene trap XG164, BayGenomics
MGI:4127030
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dusp4Gt(XG164)Byg/Dusp4Gt(XG164)Byg B6.129P2-Dusp4Gt(XG164)Byg MGI:5308078


Genotype
MGI:5308078
hm1
Allelic
Composition
Dusp4Gt(XG164)Byg/Dusp4Gt(XG164)Byg
Genetic
Background
B6.129P2-Dusp4Gt(XG164)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dusp4Gt(XG164)Byg mutation (1 available); any Dusp4 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• thymocyte development and thymic positive selection is largely normal
• regulatory T cell development is normal
• 2-fold in stimulated CD4+ T cells
• however, mice exhibit normal CD8+ T cell proliferation and Th1/Th2 hapten responses
• marginally in the lymph node
• in cells from ovalbumin-treated mice

hematopoietic system
• 2-fold in stimulated CD4+ T cells
• however, mice exhibit normal CD8+ T cell proliferation and Th1/Th2 hapten responses
• marginally in the lymph node

cellular
• 2-fold in stimulated CD4+ T cells
• however, mice exhibit normal CD8+ T cell proliferation and Th1/Th2 hapten responses





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory