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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rab1aGt(XB498)Byg
gene trap XB498, BayGenomics
MGI:4125357
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rab1aGt(XB498)Byg/Rab1aGt(XB498)Byg B6.129P2-Rab1aGt(XB498)Byg MGI:7398197
ht2
 		Rab1aGt(XB498)Byg/Rab1a+ B6.129P2-Rab1aGt(XB498)Byg MGI:7398220


Genotype
MGI:7398197
hm1
Allelic
Composition		 Rab1aGt(XB498)Byg/Rab1aGt(XB498)Byg
Genetic
Background		 B6.129P2-Rab1aGt(XB498)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab1aGt(XB498)Byg mutation (0 available); any Rab1a mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:322487 )
• homozygotes die between E10.5 to E11.5




Genotype
MGI:7398220
ht2
Allelic
Composition		 Rab1aGt(XB498)Byg/Rab1a+
Genetic
Background		 B6.129P2-Rab1aGt(XB498)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab1aGt(XB498)Byg mutation (0 available); any Rab1a mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:322487 )
• heterozygotes are viable and exhibit normal weight and fertility over a 12-month observation period; after LPS challenge, no significant differences are detected in serum levels of inflammatory cytokines or in survival relative to wild-type controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory