Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sf1Gt(XD130)Byg mutation
(0 available);
any
Sf1 mutation
(40 available)
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mortality/aging
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• no embryos are observed at E.11.5 or weaning
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Allelic Composition |
Sf1Gt(XD130)Byg/Sf1+
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Genetic Background |
involves: 129P2/OlaHsd * 129S1/SvImJ * MOLF/Ei |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sf1Gt(XD130)Byg mutation
(0 available);
any
Sf1 mutation
(40 available)
|
|
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neoplasm
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• reduced Testicular germ cell tumor incidence compared with that of the control 129 consomic Chr19 MOLF strain
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reproductive system
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• reduced Testicular germ cell tumor incidence compared with that of the control 129 consomic Chr19 MOLF strain
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endocrine/exocrine glands
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• reduced Testicular germ cell tumor incidence compared with that of the control 129 consomic Chr19 MOLF strain
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnd1Ter mutation
(1 available);
any
Dnd1 mutation
(16 available)
Sf1Gt(XD130)Byg mutation
(0 available);
any
Sf1 mutation
(40 available)
|
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neoplasm
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• bilateral testicular tumor numbers decrease compared to Dnd1Ter single mutant
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• only 40% of mice develop testis tumor compared to Dnd1Ter single mutant
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endocrine/exocrine glands
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• increase in number of bilateral small testes compared to Dnd1Ter single mutant
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• bilateral testicular tumor numbers decrease compared to Dnd1Ter single mutant
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reproductive system
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• increase in number of bilateral small testes compared to Dnd1Ter single mutant
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• bilateral testicular tumor numbers decrease compared to Dnd1Ter single mutant
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• increase in number of sterile mice compared to Dnd1Ter single mutant
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