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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Slc25a17Gt(XB686)Byg
gene trap XB686, BayGenomics
MGI:4124412
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Slc25a17Gt(XB686)Byg/Slc25a17Gt(XB686)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:6515774
hm2
Slc25a17Gt(XB686)Byg/Slc25a17Gt(XB686)Byg involves: 129P2/OlaHsd * C57BL/6 * Swiss Webster MGI:6515776


Genotype
MGI:6515774
hm1
Allelic
Composition
Slc25a17Gt(XB686)Byg/Slc25a17Gt(XB686)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a17Gt(XB686)Byg mutation (1 available); any Slc25a17 mutation (71 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• Background Sensitivity: no mice with a mixed 129P2/OlaHsd and C57BL/6 background are born unlike when Swiss Webster is included in the mixed background




Genotype
MGI:6515776
hm2
Allelic
Composition
Slc25a17Gt(XB686)Byg/Slc25a17Gt(XB686)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc25a17Gt(XB686)Byg mutation (1 available); any Slc25a17 mutation (71 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• Background Sensitivity: unlike on a mixed background with only 129P2/OlaHsd and C57BL/6, mice in a mixed background including Swiss Webster exhibit normal Mendelian ratio at birth

liver/biliary system
• enlarged in mice fed a phytol-rich diet
• apoptotic bodies in mice fed a phytol-rich diet
• in mice fed a phytol-rich diet
• acute in mice fed a phytol-rich diet
• microvesicular steatosis (including increased cholesterylesters, pristanic acid, phytanic in female and males; triacylglyerol in male mice) with reduced arachidonic acid and DHA in mice fed a phytol-rich diet
• however, levels of very long chain fatty acids are normal

cardiovascular system
• enlarged in mice fed a phytol-rich diet

growth/size/body
• in mice fed a phytol-rich diet

hematopoietic system
• enlarged in mice fed a phytol-rich diet

immune system
• enlarged in mice fed a phytol-rich diet
• acute in mice fed a phytol-rich diet

cellular
• apoptotic bodies in mice fed a phytol-rich diet





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory