Analysis Tools
neoplasm
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• Background Sensitivity: mice with a C57BL6 and C3H/HeJ F1 background exhibit develop fewer polyps than mice in a congenic C57BL/6 background in the small intestine
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Allele Symbol Allele Name Allele ID |
ApcGt(XA018)Byg gene trap XA018, BayGenomics MGI:4122552 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• Background Sensitivity: mice with a C57BL6 and C3H/HeJ F1 background exhibit develop fewer polyps than mice in a congenic C57BL/6 background in the small intestine
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• small intestine
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• increased tumor multiplicity and burden of smaller sized tumors/polyps in the distal small intestine compared with ApcMin heterozygotes
• Background Sensitivity: mice on a congenic C57BL/6 background develop more polyps than mice with a C57BL6 and C3H/HeJ F1 background
• however, tumor pathology is the same as in ApcMin heterozygotes
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• increased tumor multiplicity and burden of smaller sized tumors/polyps in the small intestine compared with ApcMin heterozygotes
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• small intestine
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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