Phenotypes associated with this allele

• Allele Symbol: Gga2^{Gt(IST10483E10)Tigm}
• Allele Name: gene trap IST10483E10, Texas A&M Institute for Genomic Medicine
• Allele ID: MGI:3960314
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gga2^Gt(IST10483E10)Tigm/Gga2^Gt(IST10483E10)Tigm	involves: C57BL/6J * C57BL/6N	MGI:5424784

Genotype
MGI:5424784

hm1

• Allelic Composition: Gga2^{Gt(IST10483E10)Tigm}/Gga2^{Gt(IST10483E10)Tigm}
• Genetic Background: involves: C57BL/6J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased birth weight ( J:184229 )

• significantly smaller than their littermates at birth, but were able to feed as evidenced by the presence of milk in their stomachs

homeostasis/metabolism

hypoglycemia ( J:184229 )

• blood glucose levels obtained on postnatal day 1 averaged 28610 mg/dL (n = 12) whereas the values of the wt and het mice were 41612 mg/dL (n = 42) and 44614 mg/dL (n = 54), respectively

mortality/aging

neonatal lethality, incomplete penetrance ( J:184229 )

• 73% of the mice that were homozygous for the gene trap insertion died within the first 48 hours of birth

postnatal lethality, complete penetrance ( J:184229 )

• all but one of the mice surviving the neonatal period died within the first three weeks